Solan, August 25
A talk on “Paradigm shift in techniques for computer-aided drug design and development” was delivered by Prof. Madhu Chopra Coordinator, Bioinformatics Facility at Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, on the second day of the DST STUTI ICT programme being conducted in Shoolini University.
She discussed QSAR models and a case study of Histone deacetylase PAN inhibitor and its role in cancer. She also discussed drug repurposing against SARS-CoV 2 and role of artificial intelligence and machine learning in Drug design and discovery.
Dr. Vinod Chaudhari, Principal Scientist of the CSIR’s Institute of Microbial Technology, Chandigarh talked about an overview of the drug discovery process from the perspective of a medicinal chemist. He discussed the role of Remdesivir in COVID-19 and its mechanism of action and gave an overview of pyrazolo-pyridine chemotypes.
Dr. Deepak Kumar, Associate professor, Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University delivered the talk on design and synthesis of heterocyclic compound, retrosynthetic analysis of the compound and total synthesis of natural compounds and their role in drug discovery process.
Third day of the training got underway with talk by Dr. S.S.V. Ramasastry, Associate Professor and swarnajayanti Fellow, Department of Chemical Sciences, IISER Mohali, India on the Relevance of Catalysis to Organic Synthesis and Subsequently to Drug Discovery who flashed High demand of organocatalytic reaction in industries, buckwald’s coupling and Suzuki coupling reaction importance from industrial perspective.
Dr. Manjunath Ghate, Professor and dean School of pharmacy, National Forensic Science University Gandhinagar, Gujarat gave the lecture on drug design and synthesis of small molecules of anticancer activity.
Dr. Upendra Sharma, Senior Scientist, CSIR-Institute of Himalayan Bioresource Technology in Palampur, gave a general overview of Traditional knowledge: Medicinal plants; bioactive molecules, and how the natural product is designed from traditional way to the final structure.
Dr Mandar Bodas (Solution consultant, Research solutions- Life Sciences Elsevier) gave lecture on Reaxys predictive retrosynthesis and their use in designing of various possible roots of reaction. In the practical session hands on several extraction techniques including, Soxhlet extraction was performed.
